377980

Hispidin

A potent, cell permeable, and reversible inhibitor of protein kinase Cβ isoform (PKCβ; IC₅₀ = 2 µM).

• 同義詞: Hispidin, 6-(3,4-Dihydroxystyrl)-4-hydroxy-2-pyrone
• 經驗公式（希爾表示法）: C₁₃H₁₀O₅
• CAS號碼: 555-55-5
• 分子量：: 246.22
• MDL號碼: MFCD01866972
• 分類程式碼代碼: 12352200

屬性

• 品質等級: 100
• 化驗: ≥90% (HPLC)
• 形狀: powder
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: yellow
• 溶解度: DMSO: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C
• InChI: 1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,15-17H/b3-1+
• InChI 密鑰: QISBNGLMCHHHFG-HNQUOIGGSA-N

描述

一般說明

A potent, cell permeable, and reversible inhibitor of protein kinase Cβ isoform (PKC_β; IC₅₀ = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.

A potent, cell permeable, and reversible inhibitor of protein kinase C_β isoform (PKC_β; IC₅₀ = 2 µM). Has stronger cytotoxic effects on cancer cells than on normal cells in vitro.

生化／生理作用

Cell permeable: yes

Primary Target
PKCβ

Product does not compete with ATP.

Reversible: yes

Target IC₅₀: 2 µM against PKCβ

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Gonindard, C., et al. 1997. Cell Biol. Toxicol. 13, 141.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: No data available
• 閃點（°C）: No data available