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Merck
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重要文件

07-817

Sigma-Aldrich

Anti-phospho-Glycogen Synthase(Ser641/Ser645) Antibody

Upstate®, from rabbit

同義詞:

Glycogen synthase 1, GYS1, GS

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human, mouse

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pSer641/pSer645)

基因資訊

human ... GYS1(2997)

特異性

Glycogen Synthase phosphorylated on serine residues 641 and 645
Predicted to cross-react with rat based on sequence homology (100%), but have not been tested.

免疫原

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-Glycogen Synthase (Ser641/Ser645).

應用

Anti-phospho-Glycogen Synthase(Ser641/Ser645) Antibody is an antibody against phospho-Glycogen Synthase(Ser641/Ser645) for use in WB.
Research Sub Category
Insulin/Energy Signaling

PI3K, Akt, & mTOR Signaling

品質

Routinely evaluated by immunoblot.

標靶描述

85 kDa

外觀

Affinity purified rabbit polyclonal IgG in Dulbecco’s PBS, pH 7.3 with 1.0 mg/mL BSA, 0.05% sodium azide, and 50% glycerol.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Laura Marr et al.
Nature communications, 13(1), 3372-3372 (2022-06-12)
Glycogen is the major glucose reserve in eukaryotes, and defects in glycogen metabolism and structure lead to disease. Glycogenesis involves interaction of glycogenin (GN) with glycogen synthase (GS), where GS is activated by glucose-6-phosphate (G6P) and inactivated by phosphorylation. We
C T Shearn et al.
Biochemistry, 50(19), 3984-3996 (2011-03-29)
The production of reactive aldehydes such as 4-hydroxy-2-nonenal (4-HNE) is a key component of the pathogenesis in a spectrum of hepatic diseases involving oxidative stress such as alcoholic liver disease (ALD). One consequence of ALD is increased insulin resistance in
Cole D Davidson et al.
Journal of the Endocrine Society, 5(8), bvab102-bvab102 (2021-07-15)
Thyroid cancer is the most common endocrine malignancy, and the global incidence has increased rapidly over the past few decades. Anaplastic thyroid cancer (ATC) is highly aggressive, dedifferentiated, and patients have a median survival of fewer than 6 months. Oncogenic
Paras S Minhas et al.
Nature, 590(7844), 122-128 (2021-01-22)
Ageing is characterized by the development of persistent pro-inflammatory responses that contribute to atherosclerosis, metabolic syndrome, cancer and frailty1-3. The ageing brain is also vulnerable to inflammation, as demonstrated by the high prevalence of age-associated cognitive decline and Alzheimer's disease4-6.

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