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Merck
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重要文件

07-503

Sigma-Aldrich

Anti-p40-phox Antibody

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, human

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... NCF4(4689)
rat ... Ncf4(500904)

特異性

p40-phox

免疫原

C-terminal 6HIS-tagged fusion protein corresponding to full length human p40-phox

應用

Anti-p40-phox Antibody is an antibody against p40-phox for use in WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

品質

routinely evaluated by immunoblot in RIPA lysates of HL-60 cells.

標靶描述

40kDa

外觀

Protein A purified
Format: Purified
Protein A purified antibody in 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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F B Wientjes et al.
The Biochemical journal, 296 ( Pt 3), 557-561 (1993-12-15)
The NADPH oxidase generates superoxide in phagocytic cells. It is important for immunity and its deficiency leads to chronic granulomatous disease (CGD). It consists of a membrane-bound flavocytochrome b that lies dormant until activated by the translocation to the plasma
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin.
Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH.
Molecular Biology of the Cell null
A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis.
Li, XJ; Tian, W; Stull, ND; Grinstein, S; Atkinson, S; Dinauer, MC
Molecular Biology of the Cell null
Anna-Lena Neehus et al.
Journal of clinical immunology, 42(6), 1244-1253 (2022-05-19)
Autosomal recessive (AR) PKCδ deficiency is a rare inborn error of immunity (IEI) characterized by autoimmunity and susceptibility to bacterial, fungal, and viral infections. PKCδ is involved in the intracellular production of reactive oxidative species (ROS). We studied a 5-year
Hassan Dakik et al.
Antioxidants (Basel, Switzerland), 10(3) (2021-04-04)
In acute myeloid leukemia (AML), a low level of reactive oxygen species (ROS) is associated with leukemic stem cell (LSC) quiescence, whereas a high level promotes blast proliferation. ROS homeostasis relies on a tightly-regulated balance between the antioxidant and oxidant

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