T-072

Tadalafil solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₂H₁₉N₃O₄
• CAS號碼: 171596-29-5
• 分子量：: 389.40
• EC號碼: 200-835-2
• MDL號碼: MFCD07771966
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329826616
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in acetonitrile
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: O=C1N(C)CC(N2[C@H](C3=CC(OCO4)=C4C=C3)C5=C(C(C=CC=C6)=C6N5)C[C@@]21[H])=O
• InChI: 1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
• InChI 密鑰: WOXKDUGGOYFFRN-IIBYNOLFSA-N
• 基因資訊: human ... PDE5A(8654)

描述

一般說明

Tadalafil is an erectile-dysfunction drug marketed under the trade name Cialis^®. This Certified Spiking Solution^® is suitable for use in numerous testing applications such as clinical toxicology, forensic analysis, urine drug testing, or calibrator preparation.

應用

• Universal Quantitation of PDE5 Inhibitors: A study highlights the use of high-performance liquid chromatography with charged aerosol detection to universally quantitate undeclared phosphodiesterase-5 inhibitors, including tadalafil, in herbal dietary supplements. This method ensures the integrity of dietary supplements and protects consumers from potential health risks (Poplawska et al., 2013).


• Drug Screening with 3D-Printed Electrochemical Cells: Research developed a multi-sensor compatible 3D-printed electrochemical cell for voltammetric drug screening, applicable to tadalafil and other drugs. This innovative approach enhances drug analysis efficiency and accuracy, facilitating rapid screening in pharmaceutical research (Ferreira et al., 2021).


• Solid Dispersions for Enhanced Solubility: A study on the physical stability of solid dispersions of tadalafil in PVP-VA investigates the thermodynamic solubility of the drug, critical for improving bioavailability in pharmaceutical formulations. This research contributes to the development of more effective and reliable drug delivery systems (Wlodarski et al., 2015).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Cialis is a registered trademark of Eli Lilly and Co.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H302 + H312 + H332,H319
• 防範說明: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 35.6 °F - closed cup
• 閃點（°C）: 2 °C - closed cup