S-010

Sildenafil solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₂₂H₃₀N₆O₄S
• CAS號碼: 139755-83-2
• 分子量：: 474.58
• EC號碼: 200-659-6
• MDL號碼: MFCD00867528
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329824411
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: pharmaceutical (small molecule)
• 形式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: O=C1NC(C2=C(OCC)C=CC(S(=O)(N3CCN(C)CC3)=O)=C2)=NC4=C1N(C)N=C4CCC
• InChI: 1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
• InChI 密鑰: BNRNXUUZRGQAQC-UHFFFAOYSA-N
• 基因資訊: human ... PDE5A(8654)

描述

一般說明

Sildenafil is a treatment for erectile dysfunction and pulmonary arterial hypertension. Sold under the trade name Viagra^®, sildenafil has a history of abuse, including by athletes as a performance enhancing drug. This Certified Spiking Solution^® is applicable for use in urine drug testing, sports testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

應用

• Effect of topical sildenafil on wound healing and oxidative stress in rats: This study investigates the application of sildenafil in a topical solution form to enhance wound healing and reduce oxidative stress in a rat model, providing insights into its potential therapeutic applications (Tunc and Ercan, 2024).


• The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications: Research assesses the compatibility of sildenafil solution when combined with various parenteral medications used in neonatal intensive care, suggesting its safe and effective integration for clinical use (De Silva et al., 2024).


• Changes in Pulmonary Vascular Resistance and Obstruction Score Following Acute Pulmonary Embolism: This study uses sildenafil in a model of acute pulmonary embolism in pigs to evaluate its effects on pulmonary vascular resistance and obstruction, highlighting its potential in managing this condition (Merit et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Viagra is a registered trademark of Pfizer, Inc.

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup