C-164

肌酸酐 盐酸盐 溶液

2.0 mg/mL in methanol: water (1:1), certified reference material, ampule of 1 mL, Cerilliant^®

• 經驗公式（希爾表示法）: C₄H₇N₃O
• CAS號碼: 60-27-5
• 分子量：: 113.12
• MDL號碼: MFCD00003203
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 2.0 mg/mL in methanol: water (1:1)
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: pharmaceutical (small molecule)
• 形式: single component solution
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• InChI: 1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)
• InChI 密鑰: DDRJAANPRJIHGJ-UHFFFAOYSA-N

描述

一般說明

Creatinine is excreted at fairly constant rates in the absence of renal disease and commonly used as benchmark in urinary biomarker analysis. Serum creatinine levels are useful indicators of renal function and have been implicated in diabetes, cardiovascular and circulatory diseases. A certified Snap-N-Spike^® solution suitable for use as starting material in calibrators and controls in creatine LC/MS or GC/MS testing methods for clinical diagnostic, urine drug testing or forensic analysis applications.

應用

• Creatinine solution in renal function research: Creatinine solution is utilized extensively as a high-purity standard for calibrating assays that measure kidney function, aiding in the diagnosis and monitoring of renal health. Its application is crucial in clinical settings for evaluating glomerular filtration rate (GFR) and kidney disease progression (Xing et al., 2024).


• Creatinine for biochemical assays: As a stable biochemical reagent, creatinine solution is employed in various enzymatic assays and biochemical studies to understand creatinine metabolism and its implications in health and disease. This research-grade creatinine aids in the development of more accurate and sensitive diagnostic techniques (Lowe-Jones et al., 2024).


• Use in scientific experiments: Creatinine solution is vital in scientific research for creating controlled experimental conditions, particularly in studies focusing on the biochemical pathways involving creatinine and its impact on cellular processes. It serves as a critical component in metabolic studies and cellular biology (Wowk et al., 2024).


• Pharmaceutical research applications: In pharmaceutical research, creatinine solutions are used as standards in the development and validation of pharmacokinetic models. These models help in understanding how drugs influence creatinine levels in the body, which is crucial for the safe and effective use of numerous medications (Carvalho Pereira et al., 2024).


• Renal pathology studies: The application of creatinine solutions in renal pathology helps in assessing the impact of various conditions on kidney function. It is particularly useful in studies where precise measurements of creatinine are necessary to determine the effect of therapeutic interventions or disease progression on renal health (Shao et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H226,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 75.2 °F
• 閃點（°C）: 24 °C