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860501P

Avanti

C22神经酰胺(d18:1/22:0)

Avanti Research - A Croda Brand 860501P, powder

同義詞:

N-二十二烷酰-D-赤-鞘氨醇

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About This Item

經驗公式(希爾表示法):
C40H79NO3
CAS號碼:
分子量::
622.06
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (860501P-10mg)
pkg of 1 × 5 mg (860501P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 860501P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

一般說明

C22神经酰胺(d18:1/22:0)或N-山嵛酰-D-赤型-鞘氨醇是一种人工合成的、由鞘氨醇和山嵛酸组成的神经酰胺。

應用

C22神经酰胺(d18:1/22:0)已用于:
  • 作为标准品,用于通过高效液相色谱/串联质谱(LC/MS2)技术测定肌肉组织样品中的神经酰胺浓度
  • 作为鞘脂代谢物的定量分析标准品
  • 研究其对线粒体-胞浆应激反应(MCSR)诱发的影响

生化/生理作用

神经酰胺在细胞分化、增殖和凋亡调节中起重要作用。还能调节应激和炎症反应。

包裝

5 mL棕色玻璃螺旋盖样品瓶(860501P-10mg)
5 mL棕色玻璃螺旋盖样品瓶(860501P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析證明 (COA)

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Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Donato A Rivas et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(11), 1727-1736 (2012-10-09)
One of the most fundamental adaptive physiological events is the response of skeletal muscle to high-intensity resistance exercise, resulting in increased protein synthesis and ultimately larger muscle mass. However, muscle growth in response to contraction is attenuated in older humans.
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor

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