推薦產品
化驗
>99% (TLC)
形狀
methanol solution
包裝
pkg of 1 × 1 mL (860076W-100ug)
製造商／商標名
Avanti Research™ - A Croda Brand 860076W
濃度
0.1 mg/mL
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC([2H])(C([2H])([2H])[2H])[2H])=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C3)[C@H]2O)O[C@@H]4O[C@H](C
一般說明
Gangliosides are glycosphingolipids, contains one or more residues of sialic acid. They are grouped according to the number of their sialic acid residues: one (M), two (D), or three (T). The GM1 ganglioside denotes a glycolipid that contains a monosialylated tetraose oligosaccharide (Galβ1 & 3GalNAcβ1 & 4(NeuAcα2 & 3)Galβ1 & 4Glcβ1 & 1′Cer). C18:0 GM1 ganglioside contains stearic acid as one of the fatty acid chain. These are normal components of the plasma membranes of mammalian cells and are abundant in neuronal membranes. Structurally, they possess the oligosaccharide chain constituting the hydrophilic portion in the extracellular medium and the ceramide moiety constituting the hydrophobic portion in the lipid layer of the membrane. The length and degree of unsaturation of both alkyl chains present in the ganglioside influences membrane fluidity and permeability. The ceramide portion regulates the activity of membrane-associated proteins.
生化／生理作用
Gangliosides plays an important role in cell-cell recognition, cell adhesion, contact inhibition, and tissue differentiation. GM1 ganglioside binds the cholera toxin.
包裝
2 mL Amber Glass Sealed Ampule
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes,Central nervous system
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
49.5 °F
閃點（°C）
9.7 °C
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Cyclic AMP accumulation in HeLa cells induced by cholera toxin. Involvement of the ceramide moiety of GM1 ganglioside.
Masserini M, et al.
The Biochemical Journal, 271(1), 107-111 (1990)
Preparation of GM1 ganglioside molecular species having homogeneous fatty acid and long chain base moieties.
Sonnino S, et al.
Journal of Lipid Research, 26(2), 248-257 (1985)
Structural characterization of the GM1 ganglioside by infrared multiphoton dissociation, electron capture dissociation, and electron detachment dissociation electrospray ionization FT-ICR MS/MS.
McFarland MA, et al.
Journal of the American Society For Mass Spectrometry, 16(5), 752-762 (2005)
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