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Key Documents

860403C

Avanti

16:0-d31-18:1 PS

Avanti Research - A Croda Brand 860403C

同義詞:

1-palmitoyl-d31-2-oleoyl-sn-glycero-3-[phospho-L-serine] (sodium salt)

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About This Item

經驗公式(希爾表示法):
C40H44NO10PNaD31
CAS號碼:
分子量::
815.18
分類程式碼代碼:
12352100
NACRES:
NA.12

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (860403C-10mg)

製造商/商標名

Avanti Research - A Croda Brand 860403C

濃度

10 mg/mL (860403C-10mg)

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([

InChI

1S/C40H76NO10P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(43)51-36(34-49-52(46,47)50-35-37(41)40(44)45)33-48-38(42)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h17-18,36-37H,3-16,19-35,41H2,1-2H3,(H,44,45)(H,46,47);/q;+1/p-1/b18-17-;/t36-,37+;/m1./s1/i2D3,4D2,6D2,8D2,10D2,12D2,14D2,16D2,19D2,21D2,23D2,25D2,27D2,29D2,31D2;

InChI 密鑰

RQYKXRYGZHMUSU-XETPNRLVSA-M

一般說明

16:0-d31-18:1 PS is a deuterated phosphatidylserine (PS), a glycerophospholipid and a natural phospholipid nutrient. It is a vital part of the cell membrane. PS is present in the brain, lungs, heart, liver and skeletal muscle.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

應用

16:0-d31-18:1 PS has been used as an internal standard to quantify fatty acid methyl esters (FAMES) using electrospray ionization tandem mass spectrometry (ESI-MS/MS)-based lipidomic analysis.

生化/生理作用

Phosphatidylserine (PS) is implicated in apoptosis and blood clotting. It controls the activity of receptors, ion channels, enzymes and signaling molecules. PS also regulates membrane fluidity. It exhibits ergogenic properties and represses muscle soreness in athletes.

包裝

5 mL Clear Glass Sealed Ampule (860403C-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome
Makarova M, et al.
Current Biology (2020)
Sensing phosphatidylserine in cellular membranes
Kay JG and Grinstein S
Sensors, 11(2) (2011)
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
Starks MA, et al.
Journal of the International Society of Sports Nutrition, 5(1), 11-11 (2008)
Yaxi Wang et al.
The Journal of cell biology, 219(5) (2020-04-19)
The yeast phosphatidylserine (PtdSer) decarboxylase Psd2 is proposed to engage in a membrane contact site (MCS) for PtdSer decarboxylation to phosphatidylethanolamine (PtdEtn). This proposed MCS harbors Psd2, the Sec14-like phosphatidylinositol transfer protein (PITP) Sfh4, the Stt4 phosphatidylinositol (PtdIns) 4-OH kinase
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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