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850371C

Avanti

22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine, chloroform

同義詞:

1,2-didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)

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About This Item

經驗公式(希爾表示法):
C52H104NO8P
CAS號碼:
分子量::
902.36
MDL號碼:
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850371C-25mg)
pkg of 1 × 20 mL (850371C-500mg)

製造商/商標名

Avanti Research - A Croda Brand 850371C

濃度

10 mg/mL (850371C-25mg)
25 mg/mL (850371C-500mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[P](=O)([O-])(OCC[N+](C)(C)C)OCC(OC(=O)CCCCCCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCCCCC

InChI

1S/C52H104NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h50H,6-49H2,1-5H3

InChI 密鑰

HRTBOPUWPUXROO-UHFFFAOYSA-N

一般說明

Phosphatidylcholines are phospholipids, that are abundantly present in the membrane. They have fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol with the help of ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

應用

22:0 PC may be used:
  • to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP)/α-secretase activity
  • to prepare a lipid monolayer to study whether ligand is specifically targeted to domains containing Cu(II)-iminodiacetate lipid (Cu-PSIDA)
  • as a lipid standard for the quantification of lipid species from lipid droplets by hydrophilic interaction liquid chromatography-high performance liquid chromatography (HILIC-HPLC)

生化/生理作用

The physical properties of membranes can be modulated with the help of fatty acyl configuration of phosphatidylcholines. They act as a vital source for eicosanoids.

包裝

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850371C-500mg)
5 mL Clear Glass Sealed Ampule (850371C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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Marcus O W Grimm et al.
International journal of molecular sciences, 14(3), 5879-5898 (2013-03-15)
Alzheimer's disease (AD) is characterized by extracellular accumulation of amyloid-β peptide (Aβ), generated by proteolytic processing of the amyloid precursor protein (APP) by β- and γ-secretase. Aβ generation is inhibited when the initial ectodomain shedding is caused by α-secretase, cleaving

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