880120C

18:0 PEG2000 PE

Avanti Research^™ - A Croda Brand 880120C

• 同義詞: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
• CAS號碼: 474922-77-5
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 形狀: liquid
• 包裝: pkg of 1 × 2.5 mL (880120C-25mg); pkg of 1 × 20 mL (880120C-500mg); pkg of 2 × 4 mL (880120C-200mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 880120C
• 濃度: 10 mg/mL (880120C-25mg); 25 mg/mL (880120C-200mg); 25 mg/mL (880120C-500mg)
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]
• InChI: 1S/C133H264NO55P.H3N/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-131(135)186-128-130(189-132(136)35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-5-2)129-188-190(138,139)187-37-36-134-133(137)185-127-126-184-125-124-183-123-122-182-121-120-181-119-118-180-1
• InChI 密鑰: QSWJINHFEMDVEM-OJCMNYADSA-N

描述

一般說明

18:0 PEG2000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000], is a modified phospholipid containing a 2000-Da PEG moiety in the polar head.

應用

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt (DSPE-PEG1) has been used to conjugate PEG onto residual amine groups on the surfaces of the functionalized TaO nanoparticles. DSPE-PEG1 may be used as a surfactant for homeotropic anchoring of the mesogen molecules. It may also be used in preparation of Nano formulations.

生化／生理作用

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to facilitate the formation of sterically stabilized liposomes (SSL). These liposomes have low reticuloendothelial system (RES) uptake and they prolong the circulating plasma half-life of the drug. The plasma half-life of the drug can be tuned from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.

包裝

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880120C-500mg)

5 mL Clear Glass Sealed Ampule (880120C-200mg)

5 mL Clear Glass Sealed Ampule (880120C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 防範說明: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危險分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 標靶器官: Central nervous system, Liver,Kidney
• 儲存類別代碼: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: does not flash
• 閃點（°C）: does not flash