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Key Documents

850368P

Avanti

20:0 PC

1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

同義詞:

1,2-dieicosanoyl-sn-glycero-3-phosphocholine; PC(20:0/20:0)

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About This Item

經驗公式(希爾表示法):
C48H96NO8P
CAS號碼:
分子量::
846.25
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 200 mg (850368P-200mg)
pkg of 1 × 25 mg (850368P-25mg)
pkg of 1 × 500 mg (850368P-500mg)

製造商/商標名

Avanti Research - A Croda Brand 850368P

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C48H96NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-47(50)54-44-46(45-56-58(52,53)55-43-42-49(3,4)5)57-48(51)41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h46H,6-45H2,1-5H3/t46-/m1/s1

InChI 密鑰

YKIOPDIXYAUOFN-YACUFSJGSA-N

一般說明

Phosphatidylcholine, a major source of diacylglycerol (DAG) is considered as a biological membrane lipid. 20:0 PC is a zwitterionic lipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

應用

20:0 PC may be used:
  • in the preparation of liposomes
  • to prepare vesicles or supported bilayer to study its ability in spontaneously forming distinct lipid domains, rafts and/or asymmetric bilayers along with other phosphatidylcholine lipids
  • to prepare small unilamellar vesicles (SUVs) to study the effect of hydrophobic mismatch on gramicidin conformation and organization

生化/生理作用

Phosphatidylcholine (PC) can serve as a surfactant in the mucus.

包裝

20 mL Clear Glass Screw Cap Vial (850368P-500mg)
5 mL Amber Glass Screw Cap Vial (850368P-200mg)
5 mL Amber Glass Screw Cap Vial (850368P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Second Messengers
Cell Biology, 443-462 (2017)
Inflammatory Bowel Disease
Integrative Medicine, 501-516 (2018)
Markus Ritter et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 32(1), 46-52 (2013-07-23)
We investigated if mixtures of the phosphatidylcholine (PC) lipids 1,2-dilauroyl-sn-glycero-3-phosphocholine (C12:0 PC; DLPC) and 1,2-diarachidoyl-sn-glycero-3-phosphocholine (C20:0 PC; DAPC), which differ by eight methylene groups in acyl chain length, lead to the spontaneous formation of distinct lipid rafts and asymmetric bilayers.
Federico Battisti et al.
Frontiers in immunology, 8, 1179-1179 (2017-10-11)
Dendritic cells (DCs) are the only antigen-presenting cells able to prime naïve T cells and cross-prime antigen-specific CD8+ T cells. Their functionality is a requirement for the induction and maintenance of long-lasting cancer immunity. Albeit intensively investigated, the in vivo
Jamie L Betker et al.
Journal of pharmaceutical sciences (2020-02-01)
Nanoparticle-mediated drug delivery has long utilized PEGylation as a mechanism for reducing uptake by the reticuloendothelial system and extending circulation lifetimes. However, studies over the past 2 decades have established that immune responses to PEG can promote clearance on repeat injection

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