CF0014

Phenylsulfanyltetrafluorobromoethane

• 線性公式: C₈H₅BrF₄S
• CAS號碼: 83015-33-2
• MDL號碼: MFCD27996155
• 分類程式碼代碼: 12352101
• NACRES: NA.22

屬性

• 形狀: liquid
• 反應適用性: reaction type: C-C Bond Formation

描述

應用

Phenylsulfanyltetrafluoroethyl bromide is a fluoroalkylbromide that is a radical source of the phenylsulfanyltetrafluoroethyl moiety. Alternatively, it can also be selectively metallated at the fluorinated carbon with Turbo Grignard reagent at low temperatures resulting in a thermally unstable anion that can act as a nucleophilic fluoroalkylation reagent towards a wide variety of electrophiles, such as aldehydes, ketones or sulfonylimines. A phenylsulfanyltetrafluoroethyl moiety incorporated in the substrate can be treated with tributyltin hydride and generate the corresponding fluoroalkyl radical. If the substrate lacks any olefins, it can be reduced to tetrafluoroethyl group whereas if the substrate contains an olefin in a correct spatial orientation, it can lead to an intramolecular cyclization affording tetrafluorinated cyclic structures.

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其他說明

Technology Spotlight: Fluoroalkylation: Expansion of Togni Reagents

法律資訊

Product of CF Plus Chemicals.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319,H413
• 防範說明: P273 - P305 + P351 + P338
• 危險分類: Aquatic Chronic 4 - Eye Irrit. 2
• 儲存類別代碼: 10 - Combustible liquids
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable