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Merck
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重要文件

C011

Sigma-Aldrich

顺式-2-甲基-5-三甲基铵甲基-1,3-氧硫杂环戊烷碘化物

同義詞:

OXA-22

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About This Item

經驗公式(希爾表示法):
C8H18INOS
CAS號碼:
分子量::
303.20
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

顏色

yellow

溶解度

H2O: soluble
methanol: soluble

SMILES 字串

[I-].C[C@H]1O[C@H](CS1)C[N+](C)(C)C

InChI

1S/C8H18NOS.HI/c1-7-10-8(6-11-7)5-9(2,3)4;/h7-8H,5-6H2,1-4H3;1H/q+1;/p-1/t7-,8-;/m0./s1

InChI 密鑰

TWNAKQKXXMGYQT-WSZWBAFRSA-M

生化/生理作用

强效毒蕈碱型乙酰胆碱受体激动剂。

注意

感光性

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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R M Eglen et al.
Naunyn-Schmiedeberg's archives of pharmacology, 342(4), 394-399 (1990-10-01)
1. para-Fluoro-hexahydrosila-difenidol (p-F-HHSiD) has been proposed as an M3 selective antagonist. However, the M3 selectivity is variable in that it exhibits a high pA2 value for M3 muscarinic receptors in guinea-pig ileum but a low value at muscarinic receptors in
Zizhuo Su et al.
American journal of translational research, 12(7), 3964-3973 (2020-08-11)
Cyclophilin A (CyPA) plays an important role in the progression of atherosclerosis. Additionally, it has been reported that lysosomal function is markedly impaired in atherosclerosis induced by oxidized low-density lipoprotein (ox-LDL). As the CyPA degradation pathway remains to be elucidated
P Angeli et al.
British journal of pharmacology, 85(4), 783-786 (1985-08-01)
The efficacy and affinity of nine pentatomic cyclic muscarinic agonists were determined on the guinea-pig ileum, according to the method of Furchgott & Bursztyn (1967). The efficacy and affinity of these agonists are affected differently by structural modifications. Our results

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