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重要文件

900889

Sigma-Aldrich

苯基-2,4,6-三甲基苯甲酰基次膦酸锂

≥95%

同義詞:

LAP

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About This Item

經驗公式(希爾表示法):
C16H16LiO3P
CAS號碼:
分子量::
294.21
分類程式碼代碼:
12352128
NACRES:
NA.23

品質等級

化驗

≥95%

形狀

crystalline powder

顏色

white to off-white

儲存溫度

2-8°C

SMILES 字串

CC1=C(C(P(C2=CC=CC=C2)(O[Li])=O)=O)C(C)=CC(C)=C1

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應用

苯基-2,4,6-三甲基苯甲酰基次膦酸锂(LAP)是一种水溶性、细胞相容的I型光引发剂,可用于水凝胶或其它聚合物材料的聚合。因为其更高的水溶性、在365nm光下的更快的聚合速率、以及在400nm处的吸光度(可实现可见光聚合),该光引发剂优于Irgacure 2959,更适用于生物学应用。改进的聚合动力学使细胞能够在较低的引发剂浓度和较长波长的光下进行封装,这已被证明能够降低引发剂毒性并提高细胞活力。

特點和優勢

  • 水溶性高
  • 生物相容
  • 对可见光敏感

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Benjamin D Fairbanks et al.
Macromolecules, 44(8), 2444-2450 (2011-04-23)
Various techniques have been adopted to impart a biological responsiveness to synthetic hydrogels for the delivery of therapeutic agents as well as the study and manipulation of biological processes and tissue development. Such techniques and materials include polyelectrolyte gels that
Benjamin D Fairbanks et al.
Biomaterials, 30(35), 6702-6707 (2009-09-29)
Due to mild reaction conditions and temporal and spatial control over material formation, photopolymerization has become a valuable technique for the encapsulation of living cells in three dimensional, hydrated, biomimetic materials. For such applications, 2-hydroxy-1-[4-(2-hydroxyethoxy) phenyl]-2-methyl-1-propanone (I2959) is the most
Pui -Yan Lee et al.
Pharmaceutical research, 37(11), 220-220 (2020-10-15)
Gold porphyrin (AuP) is a complex that has been shown to be potent against various tumors. A biocompatible interpenetrating network (IPN) system comprised of polyethyleneglycol diacrylate (PEGdA) and chemically-modified gelatin has been shown to be an effective implantable drug depot
Juliana S Ribeiro et al.
Biomacromolecules, 21(9), 3945-3956 (2020-08-14)
Oral bacterial infection represents the leading cause of the gradual destruction of tooth and periodontal structures anchoring the teeth. Lately, injectable hydrogels have gained increased attention as a promising minimally invasive platform for localized delivery of personalized therapeutics. Here, an
Joshua D McCall et al.
Biomacromolecules, 13(8), 2410-2417 (2012-06-30)
Photoinitiated polymerization remains a robust method for fabrication of hydrogels, as these reactions allow facile spatial and temporal control of gelation and high compatibility for encapsulation of cells and biologics. The chain-growth reaction of macromolecular monomers, such as acrylated PEG

文章

The introduction of LAP and water-dispersible photoinitiator nanoparticles of TPO, enables the development of novel formulations for 3D bioprinting, tissue engineering applications, and device manufacturing.

相關內容

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

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