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Key Documents

81801

Sigma-Aldrich

1-丙基磷酸酐 溶液

technical, ~50% in DMF

同義詞:

1-丙基磷酸环酐 溶液, PPACA, T3P®, 丙基磷酸三环酸酐 溶液

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About This Item

經驗公式(希爾表示法):
C9H21O6P3
CAS號碼:
分子量::
318.18
Beilstein:
5079255
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

technical

形狀

solution

濃度

~50% in DMF

SMILES 字串

CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1

InChI

1S/C9H21O6P3/c1-4-7-16(10)13-17(11,8-5-2)15-18(12,14-16)9-6-3/h4-9H2,1-3H3

InChI 密鑰

PAQZWJGSJMLPMG-UHFFFAOYSA-N

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一般說明

Propylphosphonic anhydride is a highly reactive cyclic anhydride that is commonly used as a coupling agent and water scavenger.

應用

Coupling reagent for peptide synthesis; Preparation of other amides; Synthesis of esters (depsipeptides)

特點和優勢

Some of its unique features include:
  • Broad functional group tolerance
  • Low epimerization tendency
  • By-products are water-soluble
  • High yield and purity


法律資訊

T3P is a registered trademark of Archimica GmbH

訊號詞

Danger

危險分類

Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

143.6 °F

閃點(°C)

62 °C

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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H. Kessler et al.
Liebigs Ann. Chem., 1-1 (1986)
H. Wissmann
Phosph. Sulfur Relat. Elem., 30, 645-645 (1986)
M. Feigel
Journal of the American Chemical Society, 108, 181-181 (1986)
H. Wissmann et al.
Angewandte Chemie (International Edition in English), 92, 129-129 (1980)
Propylphosphonic anhydride (T3P?): an efficient reagent for the one-pot synthesis of 1, 2, 4-oxadiazoles, 1, 3, 4-oxadiazoles, and 1, 3, 4-thiadiazoles.
Augustine JK, et al.
Tetrahedron, 65(48), 9989-9996 (2009)

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