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Merck
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文件

445460

Sigma-Aldrich

HATU

97%, for peptide synthesis

同義詞:

1-[双(二甲基氨基)亚甲基]-1H-1,2,3-三唑[4,5-b]吡啶-3-氧化物六氟磷酸酯, N-[(二甲基氨基)-1H-1,2,3-三唑-[4,5-b]吡啶-1-亚甲基]-N-甲基甲铵六氟磷酸酯- N-氧化物, HATU

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About This Item

經驗公式（希爾表示法）:
C10H15F6N6OP
CAS號碼:
148893-10-1
分子量：:
380.23
MDL號碼:
MFCD27957364
分類程式碼代碼:
12352302
PubChem物質ID:
24868183
NACRES:
NA.22

product name

HATU, 97%

化驗

97%

形狀

solid

反應適用性

reaction type: Coupling Reactions

mp

183-185 °C (lit.)

應用

peptide synthesis

儲存溫度

2-8°C

SMILES 字串

F[P-](F)(F)(F)(F)F.CN(C)[C+](N(C)C)n1n[n+]([O-])c2ncccc12

InChI

1S/C10H15N6O.F6P/c1-13(2)10(14(3)4)15-8-6-5-7-11-9(8)16(17)12-15;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChI 密鑰

FKBFHOSFPRWJNV-UHFFFAOYSA-N

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相關類別

應用

用作以下反应的试剂：
Aurora A激酶抑制剂的合成
人血浆中的D-和L-酸对映体的HPLC测定
酰胺键形成反应

用作以下反应的催化剂：
选择性酰化反应
硒环化-氧化脱硒连续反应
肽偶联剂。
通过固相合成制备 N-芳基磺酰胺键合肽。

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H317,H334

危險分類

Resp. Sens. 1 - Skin Sens. 1A

安全危害

EUH044

儲存類別代碼

4.1A - Other explosive hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Pept., Proceedings of the European Peptide Symposium., ed. U. Ragnarrson, 27, 272-273 (2002)
Yi He et al.
Organic letters, 8(12), 2483-2485 (2006-06-02)
N-Acylsulfonamide safety-catch linkers are versatile tools in solid-phase organic synthesis because of their stability. This stability necessitates linker activation prior to compound cleavage. Here, we demonstrate that the N-acylsulfonamide group can react with a pi-allyl palladium complex and that these
J. Prakt. Chem./Chem.-Ztg., 340, 581-583 (1998)
Lett. Pept. Sci., 9, 119-123 (2003)
Mazen Jamous et al.
Nuclear medicine and biology, 41(6), 464-470 (2014-05-02)
The gastrin-releasing peptide receptor (GRPR) was shown to be expressed with high density on several types of cancers. Radiolabeled peptides for imaging and targeted radionuclide therapy have been developed. In this study, we evaluated the potential of statine-based bombesin antagonists
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The special need of SPPS for rapid and highly efficient coupling reagents led to the development of several new reagents starting from BOP (Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate).

COMU-Safer and More Efficient Peptide Coupling Reagent

COMU is a non-explosive coupling agent suitable for solution phase & solid phase peptide synthesis. Its activity meets or exceeds that of HATU and its water-soluble by-product are easily removed.

COMU-Safer and More Efficient Peptide Coupling Reagent

COMU is a non-explosive coupling agent suitable for solution phase & solid phase peptide synthesis. Its activity meets or exceeds that of HATU and its water-soluble by-product are easily removed.

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