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重要文件

764779

Sigma-Aldrich

聚(乙二醇)甲醚- 嵌段 -聚( D , L 丙交酯)

PEG average Mn 2,000, PDLLA average Mn 2,000

同義詞:

PEG-PDLLA

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About This Item

分類程式碼代碼:
12162002
NACRES:
NA.23

描述

n=45, m=28 (typical)
typical PEG PDI<1.1; overall PDI<1.4 (THF, PEO)

品質等級

形狀

pellets

分子量

PDLLA average Mn 2,000
PEG average Mn 2,000
average Mn 4,000 (total)

降解時間

2-4 weeks

轉變溫度

Tg 11 °C (PEG block)
Tm 244-248 °C
Tg 88 °C (PDLLA block)

蛋白質二硫鍵異構酶

≤1.4

儲存溫度

2-8°C

一般說明

嵌段共聚物胶束广泛用于药物递送领域。PEG-PDLLA是一种可生物降解的聚合物胶束,可用作疏水性药物(如紫杉醇)的载体。PEG是亲水性部分,PDLLA是疏水性部分,后者形成负载疏水性药物的胶束核心。

應用

用作控制和靶向释放疏水性抗癌药物的载体。
药物的水溶性

特點和優勢

  • 良好的生物相容性、低免疫原性和良好的降解性。
  • 通过改变嵌段共聚物链段的尺寸可以轻松调节其性能,以适合特定应用。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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