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Merck
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重要文件

747386

Sigma-Aldrich

Poly(L-lactide), thiol terminated

average Mn 2,500, PDI ≤1.2

同義詞:

mercapto PLA, mercapto PLLA, thioPLA

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About This Item

線性公式:
H(C3H4O2)nOC2H4SH
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

solid

光學活性

[α]22/D -138°, c = 0.5% in chloroform

分子量

average Mn 2,500

轉變溫度

Tm 127-137 °C

蛋白質二硫鍵異構酶

≤1.2

儲存溫度

2-8°C

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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文章

MALDI-TOF MS is a tool for confirming end group identity & transformations, verifying successful & complete conjugation. Functionalized polymers enable a quick & efficient route for synthesis of various polymer conjugates for many applications if apt end group is present.

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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