685569

(11bS)-N,N-二甲基-8,9,10,11,12,13,14,15-八氢二萘并[2,1-d:1′,2′-f][1,3,2]二噁磷杂庚英-4-胺

• 同義詞: MonoPhos Ligand
• 經驗公式（希爾表示法）: C₂₂H₂₆NO₂P
• CAS號碼: 389130-06-7
• 分子量：: 367.42
• MDL號碼: MFCD04117692
• 分類程式碼代碼: 12352005
• PubChem物質ID: 329760980
• NACRES: NA.22

屬性

• 形狀: solid
• 品質等級: 100
• 光學活性: [α]22/D 282.0°, c = 1 in chloroform
• mp: 86-94 °C
• 官能基: amine
• SMILES 字串: CN(C)P1Oc2ccc3CCCCc3c2-c4c(O1)ccc5CCCCc45
• InChI: 1S/C22H26NO2P/c1-23(2)26-24-19-13-11-15-7-3-5-9-17(15)21(19)22-18-10-6-4-8-16(18)12-14-20(22)25-26/h11-14H,3-10H2,1-2H3
• InChI 密鑰: OIZQADYWBXZQKE-UHFFFAOYSA-N

描述

應用

DSM MonoPhos Family of Highly Efficient Privileged Ligands

(11bS)-N,N-dimethyl-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-amine is a monodentate phosphoramidite (MonoPhos) chiral ligand that can be used:

• In the Cu-catalyzed synthesis of chiral 3-(arylbut-1-yn-1-yl)silane derivatives by reacting N-tosylhydrazones with silyl-substituted alkynes via asymmetric insertion.
• In the Rh-catalyzed asymmetric hydrogenation of R-isopropylcinnamic acid derivative, a key intermediate of renin inhibitor aliskiren.
• In the Rh-catalyzed conjugate addition of arylboronic acids to lactones, enones, and nitroalkenes.

法律資訊

经 DSM 授权销售，仅供研究之用。

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)