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Merck
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重要文件

552224

Sigma-Aldrich

2-氨基-5-氯苯酚

97%

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About This Item

線性公式:
H2NC6H3(Cl)OH
CAS號碼:
分子量::
143.57
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

形狀

solid

mp

145-153 °C (lit.)

官能基

chloro

SMILES 字串

Nc1ccc(Cl)cc1O

InChI

1S/C6H6ClNO/c7-4-1-2-5(8)6(9)3-4/h1-3,9H,8H2

InChI 密鑰

FZCQMIRJCGWWCL-UHFFFAOYSA-N

一般說明

2-Amino-5-chlorophenol can be synthesized from 2-chloro-5-nitrophenol via reduction. It can also be obtained from 1-chloro-4-nitrobenzene by using a bacterial strain LW1. 2-Amino-5-chlorophenol participates in the condensation reaction with acetylferrocene to afford ferrocenyl Schiff bases bearing a phenol group.

應用

2-Amino-5-chlorophenol may be used to synthesize 2-amino-5-chloromuconic semialdehyde and benzoxazole derivatives.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis and Crystal Structure of 1-Chloro-2-methyl-4-nitrobenzene.
Saeed A and Simpson J.
Crystals, 2(1), 137-143 (2012)
Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases.
Wisastra R, et al.
Bioorganic & Medicinal Chemistry, 20(12), 5027-5032 (2012)
Synthesis, characterization, and antimicrobial activity of cobalt (II), nickel (II), copper (II) and zinc (II) complexes with ferrocenyl Schiff bases containing a phenol moiety.
Abd-Elzaher MM.
Applied Organometallic Chemistry, 18(4), 149-155 (2004)
Yi Xiao et al.
Applied microbiology and biotechnology, 73(1), 166-171 (2006-04-28)
The genes encoding enzymes involved in the initial reactions during degradation of 4-chloronitrobenzene (4CNB) were characterized from the 4CNB utilizer Pseudomonas putida ZWL73, in which a partial reductive pathway was adopted. A DNA fragment containing genes coding for chloronitrobenzene nitroreductase
M Valentovic et al.
Toxicology and applied pharmacology, 161(1), 1-9 (1999-11-24)
2-Amino-5-chlorophenol is nephrotoxic through an unidentified mechanism. This study examined the in vitro toxicity of 2-amino-5-chlorophenol in renal cortical slices from Fischer 344 rats and specifically assessed induction of lipid peroxidation and depletion of renal glutathione. Renal cortical slices exposed

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