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Merck
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529249

Sigma-Aldrich

2-氯-1,3-二甲基氯化咪唑啉

for peptide synthesis

同義詞:

2-氯-4,5-二氢-1,3-二甲基-1 H -氯化咪唑, DMC

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About This Item

經驗公式（希爾表示法）:
C5H10Cl2N2
CAS號碼:
37091-73-9
分子量：:
169.05
MDL號碼:
MFCD09039290
分類程式碼代碼:
12352005
PubChem物質ID:
24877665
NACRES:
NA.22

product name

2-氯-1,3-二甲基氯化咪唑啉,

形狀

crystalline

反應適用性

reaction type: Coupling Reactions

mp

133-140 °C (lit.)

應用

peptide synthesis

SMILES 字串

[Cl-].CN1CC[N+](C)=C1Cl

InChI

1S/C5H10ClN2.ClH/c1-7-3-4-8(2)5(7)6;/h3-4H2,1-2H3;1H/q+1;/p-1

InChI 密鑰

AEBBXVHGVADBHA-UHFFFAOYSA-M

相關類別

應用

合成试剂：
标记葡萄糖作为支链寡糖合成的中间体
荧光化学传感器
1,2-二胺作为共激活剂相关精氨酸甲基转移酶 1 的抑制剂
变构葡萄糖激酶激活剂

用于合成以下物质的反应物：
伯胺中的有机叠氮化物

aza-Henry 反应试剂
用于 macroviracin A、cycloviracin B1 和环硅烷全合成的活化剂。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

分析證明 (COA)

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Journal of Organometallic Chemistry, 686, 175-182 (2003)
Ken Qin et al.
Bioorganic chemistry, 94, 103391-103391 (2019-11-26)
Thermostability of monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs), as a critical property of biotherapeutics, is important for their physicochemical processes, pharmacodynamics, and pharmacokinetics. Fc glycosylation of mAbs plays a crucial role in antibody functions including thermostability, however, due to
Alois Fürstner et al.
Journal of the American Chemical Society, 125(43), 13132-13142 (2003-10-23)
The first total synthesis of the antivirally active glycolipid cycloviracin B(1) (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C(2)()-symmetrical macrodiolide core of the target by an efficient template-directed macrodilactonization reaction promoted by
Yanzi Gou et al.
Journal of polymer science. Part A, Polymer chemistry, 51(12), 2588-2597 (2013-06-14)
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated. A library of well-defined glycopolymers has been prepared by the combination of
Shunya Takahashi et al.
The Journal of organic chemistry, 69(13), 4509-4515 (2004-06-19)
The C(2)-symmetric macrodiolide core 2 of an antiviral agent, macroviracin A (1), was constructed in a single step by the intermolecular macrodimerization of C(22)-hydroxy carboxylic acid 3 with 2-chloro-1,3-dimethylimidazolinium chloride and DMAP in the presence of sodium hydride (NaH). The
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