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重要文件

198005

Sigma-Aldrich

2-氯-1-甲基吡啶碘化物

97%

同義詞:

Mukaiyama试剂

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About This Item

經驗公式(希爾表示法):
C6H7ClIN
CAS號碼:
分子量::
255.48
Beilstein:
3572320
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

mp

200 °C (dec.) (lit.)

官能基

chloro

SMILES 字串

[I-].C[n+]1ccccc1Cl

InChI

1S/C6H7ClN.HI/c1-8-5-3-2-4-6(8)7;/h2-5H,1H3;1H/q+1;/p-1

InChI 密鑰

ABFPKTQEQNICFT-UHFFFAOYSA-M

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一般說明

2-氯-1-甲基吡啶碘化物(Mukaiyama试剂)是有机合成中的常用试剂,用于活化醇的羟基和羧酸。它可用于以相应的羧酸合成酯、内酯、酰胺、内酰胺和烯酮的衍生物。由于其毒性低、反应条件简单、价格比EDC便宜,它还可用作肽合成中的高效偶联剂。

應用

2-氯-1-甲基吡啶碘化物(CMPI)可用作:
  • 脱水剂,用于将各种醛肟转化为腈,醇转化为硫氰酸烷基酯。
  • 交联剂,用于制备用于生物医学应用的可生物降解交联透明质酸膜和明胶膜。
  • 缩合剂,用于以β氨基酸合成各种β内酰胺。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Global Trade Item Number

庫存單位GTIN
198005-100G4061838346964
198005-10G4061838762627
198005-25G4061838762634

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