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Sigma-Aldrich

Fmoc-Tyr(tBu)-OH

≥98.0% (HPLC), for peptide synthesis

同義詞:

N-(9-芴甲氧羰基)-O-叔丁基-L-酪氨酸, Fmoc-O-叔丁基-L-酪氨酸

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About This Item

經驗公式（希爾表示法）:
C28H29NO5
CAS號碼:
71989-38-3
分子量：:
459.53
Beilstein:
4216652
EC號碼:
276-262-7
MDL號碼:
MFCD00037129
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
57651043
NACRES:
NA.26

產品名稱

Fmoc-Tyr(tBu)-OH, ≥98.0% (HPLC)

化驗

≥98.0% (HPLC)

形狀

powder

光學活性

[α]20/D −29±2°, c = 1% in DMF

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

mp

153-156 °C (lit.)

應用

peptide synthesis

官能基

Fmoc

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)Oc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)cc1

InChI

1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m0/s1

InChI 密鑰

JAUKCFULLJFBFN-VWLOTQADSA-N

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相關類別

一般說明

Fmoc-Tyr(tBu)-OH也称为Fmoc-O-叔丁基-L-酪氨酸，通常用于Fmoc固相法肽合成。

應用

Fmoc-Tyr(tBu)-OH可用于通过水中固相反应合成亮氨酸-脑啡肽酰胺(Leu-Enkephalin Amide)。也用于合成氨基酸衍生物，例如Fmoc-Tyr-OAllyl。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
BCCG9943
BCCC8011
BCCB3701
BCBZ3084
BCBW7539

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Rini Roy et al.
Journal of the American Society for Mass Spectrometry, 29(6), 1086-1098 (2018-05-26)
Immunoglobulins, such as immunoglobulin G (IgG), are of prime importance in the immune system. Polyclonal human IgG comprises four subclasses, of which IgG1 and IgG2 are the most abundant in healthy individuals. In an effort to develop an absolute MALDI-ToF-MS
Chloé Guilbaud-Chéreau et al.
ACS applied materials & interfaces, 11(14), 13147-13157 (2019-03-14)
Molecular gels formed by the self-assembly of low-molecular-weight gelators have received increasing interest because of their potential applications in drug delivery. In particular, the ability of peptides and amino acids to spontaneously self-assemble into three-dimensional fibrous network has been exploited
Loay Awad et al.
Chembiochem : a European journal of chemical biology, 17(24), 2353-2360 (2016-10-28)
We present the design, synthesis, and characterization of a novel photocaged glutamine derivative (modified on the side chain of glutamine), and describe its use in enhancing peptide stability and solubility. Our results demonstrate that this approach can be used to
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
Zdenek Kukacka et al.
ChemMedChem, 13(9), 909-915 (2018-02-24)
α-Galactosidase (αGal) is a lysosomal enzyme that hydrolyses the terminal α-galactosyl moiety from glycosphingolipids. Mutations in the encoding genes for αGal lead to defective or misfolded enzyme, which results in substrate accumulation and subsequent organ dysfunction. The metabolic disease caused

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