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Sigma-Aldrich

Fmoc-Lys(Boc)-OH

≥98.0% (HPLC), for peptide synthesis

同義詞:

Nα-芴甲氧羰基-Nε-叔丁氧羰基-L-赖氨酸

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About This Item

經驗公式(希爾表示法):
C26H32N2O6
CAS號碼:
分子量::
468.54
Beilstein:
4217767
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

product name

Fmoc-Lys(Boc)-OH, ≥98.0% (HPLC)

化驗

≥98.0% (HPLC)

形狀

solid

光學活性

[α]20/D −12±1°, c = 1% in DMF

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

應用

peptide synthesis

官能基

Boc
Fmoc

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1

InChI 密鑰

UMRUUWFGLGNQLI-QFIPXVFZSA-N

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一般說明

Fmoc-Lys(Boc)-OH 是一种氨基酸衍生物,用于Fmoc固相合成多肽的试剂。

應用

Fmoc-Lys(Boc)-OH可用于:
  • 通过与甲基苯甲胺(MBHA)树脂偶联固相合成五取代的二氢咪唑基丁基二氢咪唑-3-盐。
  • 基于Fmoc多肽合成线性嵌插剂双萘四酰亚二胺
  • 合成ε-Boc-ε-(3,5-双-三氟甲基-苄基)-α-Fmoc-L-赖氨酸,可用作基于19F NMR的筛选工具。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Improved synthesis of polyfluorinated l-lysine for 19F NMR-based screening.
Malgesini B, et al.
Molecular Diversity, 13(1), 53-56 (2009)
Solid-phase parallel synthesis of substituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts.
Acharya AN, et al.
Tetrahedron Letters, 43(7), 1157-1160 (2002)
Bis-naphthalene diimide exhibiting an effective bis-threading intercalating ability.
Nojima T, et al.
Nucleic Acids Symposium Series, 3(1), 123-124 (2003)
Marta Kulik et al.
Biochimie, 138, 32-42 (2017-04-12)
A fragment of 23S ribosomal RNA (nucleotides 1906-1924 in E. coli), termed Helix 69, forms a hairpin that is essential for ribosome function. Helix 69 forms a conformationally flexible inter-subunit connection with helix 44 of 16S ribosomal RNA, and the nucleotide
Marine Bacchi et al.
Protein science : a publication of the Protein Society, 25(12), 2225-2242 (2016-09-28)
Synthetic biology (or chemical biology) is a growing field to which the chemical synthesis of proteins, particularly enzymes, makes a fundamental contribution. However, the chemical synthesis of catalytically active proteins (enzymes) remains poorly documented because it is difficult to obtain

文章

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.

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