465313

1-甲基吲哚-3-甲酸

97%

• 經驗公式（希爾表示法）: C₁₀H₉NO₂
• CAS號碼: 32387-21-6
• 分子量：: 175.18
• MDL號碼: MFCD01321244
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24870267

屬性

• 品質等級: 100
• 化驗: 97%
• mp: 197-200 °C (dec.) (lit.)
• 官能基: carboxylic acid
• SMILES 字串: Cn1cc(C(O)=O)c2ccccc12
• InChI: 1S/C10H9NO2/c1-11-6-8(10(12)13)7-4-2-3-5-9(7)11/h2-6H,1H3,(H,12,13)
• InChI 密鑰: HVRCLXXJIQTXHC-UHFFFAOYSA-N

描述

一般說明

1-Methylindole-3-carboxylic acid is an indole derivative that can be prepared by the oxidation of 1-methylindole-3-aldehyde with alkaline potassium permanganate.

應用

• Reactant for preparation of bisindolyl pyrimidinones analogs of PKC inhibitor LY333531
• Reactant for preparation of (heteroaryl)(carboxamido)arylpyrrole derivatives as Cdc7 kinase inhibitors, antitumor and antiproliferative agents
• Reactant for preparation of (pyrrolidinylmethoxy)cyclohexanecarboxylic acids as antigen-4 (VLA-4) antagonists
• Reactant for preparation of EphB3 receptor tyrosine kinase inhibitors
• Reactant for preparation of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
• Reactant for preparation of potent nonpeptidic urotensin II receptor agonists
• Reactant for preparation of pyrrolizidine esters, amides, and ureas as 5-HT4 receptor ligands

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves