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Key Documents

419591

Sigma-Aldrich

3-丁烯基溴化镁 溶液

0.5 M in THF

同義詞:

1-(溴化镁)-3-丁烯, 1-丁烯-4-基溴化镁, 3-丁烯基溴化镁, 溴-3-丁烯-1-基镁

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About This Item

線性公式:
H2C=CHCH2CH2MgBr
CAS號碼:
分子量::
159.31
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22

品質等級

反應適用性

reaction type: Grignard Reaction

濃度

0.5 M in THF

bp

65 °C

密度

0.937 g/mL at 25 °C

SMILES 字串

Br[Mg]CCC=C

InChI

1S/C4H7.BrH.Mg/c1-3-4-2;;/h3H,1-2,4H2;1H;/q;;+1/p-1

InChI 密鑰

SMLLHQBZPPSOSR-UHFFFAOYSA-M

應用

可参与钌催化剂协助的环化反应的合成结构单元。
用于由 L-酒石酸合成 (–)-muricatacin 的非对映选择性关键步骤。

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react 1

標靶器官

Central nervous system, Respiratory system

安全危害

儲存類別代碼

4.3 - Hazardous materials which set free flammable gases upon contact with water

水污染物質分類(WGK)

WGK 3

閃點(°F)

-22.0 °F - closed cup

閃點(°C)

-30 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves


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Aleksandar Ivkovic et al.
Organic letters, 6(8), 1221-1224 (2004-04-09)
The combination of alkene metathesis and beta-fragmentation offers an efficient entry into (Z)-configured medium-ring cycloalkenes. The versatility of this method is demonstrated by the total synthesis of Periplanone C, a semiochemical of Periplaneta americana. [reaction: see text]
Tetrahedron Asymmetry, 17, 2465-2465 (2006)
Toshio Honda et al.
Organic letters, 6(1), 87-89 (2004-01-03)
[reaction: see text] A diastereoselective total synthesis of securinine in optically pure form was achieved by employing ring-closing metathesis of the corresponding dienyne compound as a key step.
Jehrod B Brenneman et al.
Organic letters, 6(8), 1329-1331 (2004-04-09)
A concise synthesis of the potent nAChR agonist (+)-anatoxin-a (1) has been completed in a series of only nine chemical operations and 27% overall yield from commercially available D-methyl pyroglutamate (4). The synthesis features a novel procedure for the diastereoselective

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