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About This Item
線性公式:
[-(CH2)3CONHOH]2
CAS號碼:
分子量：:
204.22
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
推薦產品
品質等級
化驗
95%
mp
153-155 °C (lit.)
官能基
amine
SMILES 字串
ONC(=O)CCCCCCC(=O)NO
InChI
1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H,1-6H2,(H,9,11)(H,10,12)
InChI 密鑰
IDQPVOFTURLJPT-UHFFFAOYSA-N
生化／生理作用
软木肟酸(SBHA)是组蛋白脱乙酰基酶（HDAC）抑制剂。SBHA 抑制 HDAC1 和 HDAC3 的活性，IC50 值分别为 250 和 300 nM。SBHA 抑制增殖，并诱导几种癌细胞系的凋亡。研究表明，SBHA 可激活甲状腺髓样癌（MTC）细胞中的 Notch 信号传导。
相關產品
產品號碼
描述
訂價
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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