推薦產品
品質等級
反應適用性
reaction type: Grignard Reaction
濃度
1.0 M in THF
密度
1.021 g/mL at 25 °C
官能基
fluoro
SMILES 字串
Fc1ccc([Mg]Br)cc1
InChI
1S/C6H4F.BrH.Mg/c7-6-4-2-1-3-5-6;;/h2-5H;1H;/q;;+1/p-1
InChI 密鑰
QYBFFRXNNFXREA-UHFFFAOYSA-M
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應用
4-氟苯基溴化镁溶液（格氏试剂）可用作合成以下化合物的试剂：
- 帕罗西汀合成中的关键中间体。
- 通过与硫醇的交叉偶联反应生成芳基硫化物。
- 作为雄激素受体拮抗剂的4-芳基甲基-1-苯基吡唑和4-芳氧基-1-苯基吡唑衍生物。
- 用于制备阿瑞吡坦的Grignard 中间体。
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
標靶器官
Respiratory system
安全危害
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
-4.0 °F - closed cup
閃點（°C）
-20 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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