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About This Item
線性公式:
CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3
CAS號碼:
分子量：:
334.49
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
推薦產品
品質等級
化驗
97%
形狀
liquid
折射率
n20/D 1.495 (lit.)
bp
156-160 °C/0.15 mmHg (lit.)
密度
1.083 g/mL at 25 °C (lit.)
官能基
ester
thioester
SMILES 字串
CCCC(=O)OCC(CSC(=O)CCC)SC(=O)CCC
InChI
1S/C15H26O4S2/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3
InChI 密鑰
NHBKXEKEPDILRR-UHFFFAOYSA-N
應用
2,3-Dimercapto-1-propanol tributyrate is a thioester analog of triacylglycerol and has been used:
- in lipase inhibition assay during in vitro screening of medicinal plants as antidiabetics with glucosidase and lipase inhibitory activities
- in colorimetric microplate assay for lipase activity
- to analyze positional specificity of LipG (lipase-encoding gene) toward triacylglycerol by a simple continuous spectrophotometric method
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
235.4 °F - closed cup
閃點（°C）
113 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Mi-Hwa Lee et al.
Applied and environmental microbiology, 72(11), 7406-7409 (2006-09-05)
We cloned lipG, which encoded a lipolytic enzyme, from a Korean tidal flat metagenomic library. LipG was related to six putative lipases previously identified only in bacterial genome sequences. These enzymes comprise a new family. We partially characterized LipG, providing
Suk-Jung Choi et al.
Journal of biochemistry and molecular biology, 36(4), 417-420 (2003-08-05)
The present work describes a colorimetric microplate assay for lipase activity based on the reaction between 5,5'-dithiobis(2-nitro benzoic acid) (DTNB) and the hydrolysis product of 2,3-dimercapto-1-propanol tributyrate (DMPTB). Reaction mixtures containing DTNB, DMPTB, and lipase were prepared in microplate wells
[A new simplified colorimetric assay of colipase in duodenal juice using BALB as substrate and its clinical application].
Y Furukawa et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 83(7), 1367-1375 (1986-07-01)
S Lombard et al.
The Biochemical journal, 358(Pt 3), 773-781 (2001-09-06)
The present study was carried out with a view of determining ricin lipolytic activity on neutral lipids in emulsion and in a membrane-like model. Using 2,3-dimercapto-1-propanol tributyrate (BAL-TC(4)) as substrate, the lipolytic activity of ricin was found to be proportional
Guillermo Ramírez et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 701261-701261 (2012-10-20)
This work shows the inhibitory effect on glucosidase and lipase enzymes of 23 medicinal plants described as traditional treatments for diabetes in several Mexican sources. Hydroalcoholic extracts of selected plants were evaluated at 1 mg/mL for glucosidase and 0.25 mg/mL for lipase
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