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Merck

MMP14

matrix metallopeptidase 14 (membrane-inserted)

同義詞:
MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1
物種:
UniProtKB ID:
基因 ID:
  • Human(4323) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
  • Mouse(17387) matrix metallopeptidase 14 (membrane-inserted)
  • Rat(81707) matrix metallopeptidase 14 (membrane-inserted)
  • chicken(426253) matrix metallopeptidase 14 (membrane-inserted)
  • cow(281915) matrix metallopeptidase 14 (membrane-inserted)
  • Horse(100034170) matrix metallopeptidase 14 (membrane-inserted)
  • domestic cat(101089776) matrix metallopeptidase 14 (membrane-inserted)
  • dog(403823) matrix metallopeptidase 14 (membrane-inserted)
  • naked mole-rat(101723795) matrix metallopeptidase 14 (membrane-inserted)
  • Domestic Rabbit(100009598) matrix metallopeptidase 14 (membrane-inserted)
  • domestic guinea pig(100732039) matrix metallopeptidase 14 (membrane-inserted)
  • sheep(443116) matrix metallopeptidase 14 (membrane-inserted)

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Antibodies

Product Number
描述
物種活性
應用
抗MMP-14抗体,催化域,克隆LEM-2 / 15.8, clone LEM-2/15.8, Chemicon®, from mouse,
物種活性
human, mouse
應用
ELISA
immunoprecipitation (IP)

western blot
Anti-MMP-14 Antibody, serum, Chemicon®,
物種活性
human
應用
ELISA
flow cytometry

immunocytochemistry

immunoprecipitation (IP)

western blot
Anti-Human MT1-MMP catalytic domain Antibody, clone 3G4.2, clone 3G4.2, Chemicon®, from mouse,
物種活性
human
應用
immunocytochemistry
immunohistochemistry

western blot
Anti-MT1-MMP Antibody, hinge region, from rabbit, purified by affinity chromatography,
物種活性
human, rat
應用
immunohistochemistry
western blot
Anti-MMP-14 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
描述
物種
马立马司他, ≥98% (HPLC),
物種
human, rat, mouse
CP-101537, ≥98% (HPLC),
物種
human, rat, mouse
CP-471474, ≥98% (HPLC),
物種
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
物種
human, rat, mouse

Proteins

Product Number
描述
物種
MMP-14, human, prodomain, catalytic domain, and hemopexin domain, E. coli recombinant, ,
物種
human