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Merck
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重要文件

SAB4501901

Sigma-Aldrich

Anti-MMP-14 antibody produced in rabbit

affinity isolated antibody

同義詞:

MATRIX METALLOPROTEINASE 14, MEMBRANE-TYPE, MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1, MT1-MMP, matrix metalloproteinase 14 (membrane-inserted)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 65 kDa

物種活性

mouse, rat, human

濃度

~1 mg/mL

技術

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MMP14(4323)

一般說明

Anti-MMP-14 Antibody detects endogenous levels of total MMP-14 protein. Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14.

免疫原

The antiserum was produced against synthesized peptide derived from human MMP-14.

Immunogen Range: 471-520

生化/生理作用

Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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存取文件庫

Marta Smeda et al.
Oncotarget, 9(25), 17810-17824 (2018-05-01)
Platelet inhibition has been considered an effective strategy for combating cancer metastasis and compromising disease malignancy although recent clinical data provided evidence that long-term platelet inhibition might increase incidence of cancer deaths in initially cancer-free patients. In the present study
Matrix metalloproteinases in skin.
Kahari VM, Ssaarialho K
Experimental Dermatology (1997)
Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis.
Sathyamoorthy T
Journal of Immunology (2015)
Diverse matrix metalloproteinase functions regulate cancer amoeboid migration
Jose L
Nature Communications (2014)
MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo.
Ulasov I
Cancer Letters (2015)

Global Trade Item Number

庫存單位GTIN
SAB4501901-100UG4061837745034

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