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Merck

DRD4

dopamine receptor D4

同義詞:
D4DR
物種:
UniProtKB ID:
基因 ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • chicken(423016) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • dog(448805) dopamine receptor D4

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Small Molecule - Agonist

產品編號
描述
物種
PD 168,077 maleate salt, powder,
物種
human
R-(−)-阿朴吗啡 盐酸盐 半水合物, United States Pharmacopeia (USP) Reference Standard,
物種
human
罗匹尼罗 盐酸盐, powder, ≥98% (HPLC),
物種
human
普拉克索 二盐酸盐, >98% (HPLC), powder,
物種
human
罗匹尼罗 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
L-745,870 hydrochloride, ,
物種
human
U-101958 maleate salt, solid,
物種
human
L-741,626, ≥98% (HPLC),
物種
human
氯丙嗪盐酸盐标准液 盐酸盐, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
普马嗪 盐酸盐, ,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
物種活性
human, mouse, rat
應用
immunocytochemistry
western blot
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
物種活性
mouse
應用
ELISA
western blot
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
物種活性
human, rat
應用

Small Molecule - Inhibitor

產品編號
描述
物種
GBR 12909 二盐酸盐, solid, ≥98% (HPLC),
物種
human
安非他酮 盐酸盐, ≥98% (HPLC), solid,
物種
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
物種
human
阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
Amoxapine, ,
物種
human

Small Molecule - Metabolite

產品編號
描述
物種
3-羟基-4-甲氧基苯乙胺 盐酸盐, ,
物種
human
3-甲氧基酪胺 盐酸盐, ≥95.5%, crystalline,
物種
human

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
BP897, >98% (HPLC), solid,
物種
human, rat
氟哌啶醇, powder,
物種
human, rat
氯氮平标准液, ,
物種
human, rat

Small Molecule - Precursor

產品編號
描述
物種
左旋多巴, ≥98% (TLC),
物種
mouse, human, rat
3,4-二羟基- DL- 苯丙氨酸, ,
物種
mouse, human, rat