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Key Documents

M4251

Sigma-Aldrich

3-甲氧基酪胺 盐酸盐

≥95.5%, crystalline

同義詞:

3-MT, 3-甲氧基-4-羟基苯乙胺 盐酸盐, 4-(2-氨基乙基)-2-甲氧基苯酚 盐酸盐

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About This Item

線性公式:
CH3OC6H3-4-(OH)CH2CH2NH2·HCl
CAS號碼:
分子量::
203.67
Beilstein:
3631283
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥95.5%

形狀

crystalline

drug control

Home Office Schedule 1

顏色

white to light brown

mp

213-215 °C (lit.)

儲存溫度

−20°C

SMILES 字串

Cl[H].COc1cc(CCN)ccc1O

InChI

1S/C9H13NO2.ClH/c1-12-9-6-7(4-5-10)2-3-8(9)11;/h2-3,6,11H,4-5,10H2,1H3;1H

InChI 密鑰

AWRIOTVUTPLWLF-UHFFFAOYSA-N

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生化/生理作用

多巴胺的主要代谢物;儿茶酚O-甲基转移酶的产物。

特點和優勢

该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面, 请单击此处

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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N van Duinen et al.
The Journal of clinical endocrinology and metabolism, 95(1), 209-214 (2009-11-10)
Patients with head-and-neck paragangliomas (HNPGL) are regularly screened for catecholamine excess. The clinical relevance of increased urinary secretion of 3-methoxytyramine is unclear in HNPGL. The aim of the study was to assess the prevalence and the clinical, biochemical, and radiological
Bérengère Claude et al.
Analytica chimica acta, 699(2), 242-248 (2011-06-28)
Capillary electrophoresis (CE) has been investigated for the analysis of some neurotransmitters, dopamine (DA), 3-methoxytyramine (3-MT) and serotonin (5-hydroxytryptamine, 5-HT) at nanomolar concentrations in urine. Field-amplified sample injection (FASI) has been used to improve the sensitivity through the online pre-concentration
Mirko Peitzsch et al.
Annals of clinical biochemistry, 50(Pt 2), 147-155 (2013-03-21)
Measurements of plasma normetanephrine (NMN) and metanephrine (MN) provide a sensitive test for diagnosis of phaeochromocytomas and paragangliomas (PPGLs), but do not allow detection of dopamine-producing tumours. Here we introduce a novel mass spectrometric based method coupled to ultraperformance liquid
Dilo Pillai et al.
Annals of clinical biochemistry, 47(Pt 2), 137-142 (2010-02-11)
Up to 2007 there was no formal external quality assurance programme for plasma free metanephrines. A pilot programme was conceived by the AACB (Australian Association of Clinical Biochemists) Working Party on biogenic amines. With support from the AACB and Royal
N van Duinen et al.
European journal of endocrinology, 169(3), 377-382 (2013-07-09)
A substantial number of patients with head and neck paragangliomas (HNPGLs) have biochemically active tumors, evidenced by increased urinary excretion of catecholamines and metabolites, including 3-methoxytyramine (3MT). It is unclear whether plasma levels of these parameters are more sensitive to

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