推薦產品
形狀
solid
品質等級
顏色
off-white
溶解度
DMSO: 11 mg/mL
ethanol: 2.7 mg/mL
H2O: 3 mg/mL
SMILES 字串
OC(=O)\C=C/C(O)=O.CC(C)Oc1cccnc1N(C)C2CCN(CC2)Cc3ccccc3
InChI
1S/C21H29N3O.C4H4O4/c1-17(2)25-20-10-7-13-22-21(20)23(3)19-11-14-24(15-12-19)16-18-8-5-4-6-9-18;5-3(6)1-2-4(7)8/h4-10,13,17,19H,11-12,14-16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI 密鑰
KPYPLDPMBWPEBO-BTJKTKAUSA-N
基因資訊
human ... DRD4(1815)
生化／生理作用
U-101958 maleate salt is a selective D4 dopamine receptor antagonist. Studies have reported that U-101958 maleate cannot inhibit bromocriptine-mediated [3H]thymidine incorporation in opossum kidney (OK) cells.
準備報告
U-101958 maleate salt is soluble in water (at 3 mg/mL), ethanol (2.7 mg/mL), and DMSO (11 mg/mL).
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
V A Narkar et al.
Journal of the American Society of Nephrology : JASN, 12(9), 1844-1852 (2001-08-24)
This study was conducted to determine the expression of dopamine D(2)-like receptors in opossum kidney (OK) cells and to examine the potential role of these receptors in mitogenesis. First, the presence of D(2)-like receptor binding sites in OK cell membranes
Substituted aminopiperidines as selective and potent D4-dopamine receptor antagonists.
Schlachter, S.K.
Abstr. Soc. Neurosci, 21, 253-253 (1995)
S K Schlachter et al.
European journal of pharmacology, 322(2-3), 283-286 (1997-03-19)
We have discovered two substituted 4-aminopiperidine compounds having high in vitro affinity and selectivity for the human dopamine D1 receptor. Both compounds, 3-ethoxy-N-methyl-N-[1-(phenylmethyl)-4-piperidinyl]-2-pyridinylamine (U-99363E), and its 3-isopropoxy analog (U-101958), were found through a routine receptor binding screen. The determined affinities
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務