推荐产品
生物源
mouse
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
4H4, monoclonal
形狀
buffered aqueous solution
物種活性
human
技術
indirect ELISA: suitable
western blot: 1-5 μg/mL
同型
IgG1κ
GenBank登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... RHOT1(55288)
一般說明
Ras同源物家族成员T1（RHOT1）由位于人染色体 17q11.2的基因编码。RhoT1是线粒体Rho GTPase家族成员。
免疫原
带GST标签的RHOT1（NP_060777，483 a.a. ~ 580 a.a）部分重组蛋白。GST标签的分子量为26 KDa。
序列
TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP
序列
TEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVKQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYP
生化／生理作用
Ras同源物家族成员T1（RHOT1）在线粒体稳态和细胞凋亡的控制中起着至关重要的作用。RHOT1 可作为胰腺癌（PC）的肿瘤抑制基因，它被认为是总体生存率的潜在预后生物标志物，也有望成为PC治疗靶点。RHOT1表达的下降可能导致淋巴结转移（LNM）和较短的生存期。RHOT1在线粒体运输、淋巴细胞迁移和极性中发挥重要作用。
外觀
溶于pH7.4的磷酸盐缓冲盐水中的溶液
法律資訊
GenBank is a registered trademark of United States Department of Health and Human Services
免責聲明
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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