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一般說明
凝血酶是止血方面的最终凝血蛋白酶，促进促凝血和抗凝作用。
應用
凝血酶用于站点融合蛋白的位点特异性裂解，重组融合蛋白含有可进入的凝血酶识别站点，用于去除亲和标签。凝血酶已用于研究马富血小板血浆的活化。
凝血酶用于站点融合蛋白的位点特异性裂解，重组融合蛋白含有可进入的凝血酶识别站点，用于去除亲和标签。
生化／生理作用
选择性裂解纤维蛋白原中 Arg-Gly 键形成纤维蛋白和纤维蛋白肽 A 和 B 的丝氨酸蛋白酶。
單位定義
通过与 NIH 凝血酶参比标准品（批次 K）直接比较，以 NIH 单位表示活性。
外觀
从生理盐水柠檬酸钠缓冲液 (pH 6.5) 冻干
分析報告
NIH 试验程序使用 0.2ml 稀释血浆（与生理盐水 1:1）作为底物，0.1根据改进的 Biggs 方法，ml 凝血酶样本（在 1% 缓冲白蛋白溶液中稳定）。仅使用 15-25 秒范围内的凝血时间测定凝血酶浓度。
其他說明
查看更多关于 凝血酶的信息， 请访问 www.sigma-aldrich.com/enzymeexplorer。
基底
訊號詞
Danger
危險分類
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.
Thrombin Factor IIa is an endolytic serine protease that selectively cleaves the Arg--Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.
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