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生物源
synthetic (organic)
品質等級
化驗
≥97% (HPLC)
形狀
powder
技術
HPLC: suitable
顏色
white to off-white
儲存溫度
2-8°C
SMILES 字串
[Na].CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(OP(O)(O)=O)c(C)c(C)c2O1
InChI
1S/C29H51O5P.Na.H/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(34-35(30,31)32)23(5)24(6)28(26)33-29;;/h20-22H,9-19H2,1-8H3,(H2,30,31,32);;
InChI 密鑰
QRLCTLIPEFQSSG-UHFFFAOYSA-N
應用
(±)-α-生育酚磷酸酯二钠盐已被用作抗氧化剂，用于评估其对大鼠海马神经元氧化损伤的保护作用。它还被用于研究其分子机制和跨质膜运输。
生化／生理作用
生育酚（TCP）（维生素E）是一系列（α、β、γ 和δ）手性有机分子，其色原烷醇环苯酚部分的甲基化程度不同。 生育酚是脂溶性抗氧化剂，可保护细胞膜免受氧化损伤。α-生育酚是人类优先吸收的生育酚形式。α-生育酚磷酸酯 (TocP)是与α生育酚乙酸酯、α-生育酚烟酸酯、α-生育酚琥珀酸酯和其他酯化形式一起，作为相似但活性不同的维生素E增补剂。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Jean-Marc Zingg
Mini reviews in medicinal chemistry, 7(5), 543-558 (2007-05-17)
Natural vitamin E comprises 8 different analogues, the alpha-, beta-, gamma-, and delta-tocopherols and the alpha-, beta-, gamma-, and delta-tocotrienols. However, only alpha-tocopherol is selectively enriched by the liver; the other vitamin E analogues and also excess alpha-tocopherol are converted
Subhendu Mukherjee et al.
Biochimica et biophysica acta, 1782(9), 498-503 (2008-06-17)
The emerging potential of alpha-tocopheryl phosphate, a phosphoric acid ester of alpha-tocopherol, in health benefits was tested gavaging this compound (5 mg/kg body wt) to a group of rats for a period of thirty days while the control rats were
Tomohisa Mori et al.
Behavioural pharmacology, 18(8), 725-729 (2007-11-09)
Chronic morphine-induced withdrawal syndrome after morphine cessation remains a severe obstacle in the clinical treatment of morphine. Previous studies have shown that nitric oxide synthetase (NOS) inhibitors may have therapeutic potential in morphine withdrawal in humans. The mechanisms that underlie
Hitoshi Masaki et al.
Free radical research, 36(6), 705-709 (2002-08-16)
alpha-Tocopherol is a lipophilic vitamin that exhibits an antioxidative activity. The purpose of this study was to clarify the roles of alpha-tocopherol in the regulation of intracellular glutathione (GSH) levels in HaCaT keratinocytes. When HaCaT keratinocytes were cultivated with alpha-tocopherol
Marc Birringer
Molecular nutrition & food research, 54(5), 588-598 (2010-02-20)
Vitamin E is known as the most important lipid antioxidant and is widely used to prevent age-associated diseases. Despite increasing knowledge about human vitamin E metabolism, little is known to justify its widespread use. As meta-analyses revealed even harmful effects
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