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生物源
human
重組細胞
expressed in insect cells
化驗
≥85% (SDS-PAGE)
形狀
frozen liquid
分子量
~32.5 kDa
包裝
pkg of 5 μg
儲存條件
avoid repeated freeze/thaw cycles
濃度
350 μg/mL
顏色
colorless to clear
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... FGF2(2247)
應用
FGF2 (fibroblast growth factor 2)-human has been used to study the role of FGF2 on steroidogenesis and survival of cultured buffalo granulosa cells. It has been used as a control to study activated α2-macroglobulin mediated Müller glial cell migration.
生化／生理作用
Acidic fibroblast growth factor (FGF-1) and basic fibroblast growth factor (FGF-2) are ubiquitous cytokines found in many tissues. They have effects on multiple cell types derived from mesoderm and neuroectoderm, including endothelial cells. FGF proteins are small peptides of 155 to 268 amino acid residues. The degree of sequence identity between different family members is 30-60 % in a "central domain" of approx. 120 amino acids. This domain confers to FGFs a common tertiary structure and the ability to bind to heparin. Secreted FGFs signal to target cells by binding and activating cell-surface tyrosine kinase FGF receptors (FGFRs; 6, 7). The function of FGFs and FGFRs during embryonic development and adult physiology has been addressed by gain- and loss-of-function experiments in several animal model organisms. These studies have shown that FGFs act as key regulators of developmental events.
外觀
Clear and colorless frozen liquid solution
準備報告
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Fibroblast growth factor-2.
Nugent MA and Iozzo RV
The International Journal of Biochemistry & Cell Biology, 32, 115-120 (2000)
Li Liu et al.
Biomaterials, 35(24), 6259-6267 (2014-05-09)
Nanofibrous gelatin substrates are suited for long-term expansion of human pluripotent stem cells (hPSCs) under feeder- and serum-free culture conditions. A combinatorial library with different sets of processing parameters was established to assess the culture performance of hPSCs on nanofibrous
L De Moerlooze et al.
Development (Cambridge, England), 127(3), 483-492 (2000-01-13)
The fibroblast growth factor receptor 2 gene is differentially spliced to encode two transmembrane tyrosine kinase receptor proteins that have different ligand-binding specificities and exclusive tissue distributions. We have used Cre-mediated excision to generate mice lacking the IIIb form of
S R Mishra et al.
Research in veterinary science, 108, 98-111 (2016-09-25)
The present study investigated the expression and localization of FGF and its functional receptors in the follicle of buffalo and the treatment of FGF2 on mRNA expression of CYP19A1 (aromatase), PCNA, and BAX (BCL-2 associated X protein) in cultured buffalo
Isako Saga et al.
Neuro-oncology, 16(8), 1048-1056 (2014-05-27)
The metabolic preference of malignant glioma for glycolysis as an energy source is a potential therapeutic target. As a result of the cellular heterogeneity of these tumors, however, the relation between glycolytic preference, tumor formation, and tumor cell clonogenicity has
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