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Merck
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Key Documents

SRP0697

Sigma-Aldrich

TAU-316 Protein

recombinant

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.77

重組細胞

expressed in E. coli

化驗

70-95% (SDS-PAGE)

形狀

frozen liquid

分子量

~39 kDa

濃度

0.2 μg/μL

登錄號

P10636-3

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... MAPT(4137)

應用

Useful for kinase assay and Western blot.

生化/生理作用

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type (1). Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy (2).

序列

Full Length

重構

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

儲存和穩定性

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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