SML3711

DENSPM tetrahydrochloride

≥98% (HPLC)

• 别名: BE 333 HCl, BENSpm HCl, DENSpm 4HCl, N1,N11-Diethylnorspermine tetrahydrochloride, N1,N11-bis(ethyl)norspermine tetrahydrochloride
• 经验公式（希尔记法）: C₁₃H₃₂N₄· 4HCl
• CAS号: 156886-85-0
• 分子量: 390.26
• MDL號碼: MFCD00871200
• 分類程式碼代碼: 41121800
• 分類程式碼代碼: 12352200
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

DENSPM HCl is a nontoxic polyamine analog that enhances polyamine catabolism and production of hazardous hydrogen peroxide and N-acetyl-3-aminopropanal by inducing spermidine/spermine-N1-acetyl transferase (SSAT) expression. DENSPM HCl improves stem cell maintenance through reduced translation, exhibits slower proliferation rates in cancer cells, and induces autophagy. It shows greater antitumor activity and less associated toxicity in a human melanoma xenograft model.

Polyamine pathway inhibitor; potent inducer of spermidine/spermine N1-acetyltransferase

注意

Hygroscopic

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable