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SML3047

Sigma-Aldrich

Urolithin C

≥97% (HPLC)

别名:

3,8,9-Trihydroxy-6H-benzo[c]chromen-6-one, 3,8,9-Trihydroxy-6H-dibenzo[b,d]pyran-6-one, 3,8,9-Trihydroxyurolithin

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About This Item

经验公式（希尔记法）:
C13H8O5
CAS号:
165393-06-6
分子量:
244.20
MDL號碼:
MFCD20275232
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

100

化驗

≥97% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

−20°C

SMILES 字串

O=C1C2=CC(O)=C(O)C=C2C3=C(C=C(O)C=C3)O1

生化／生理作用

Urolithin C is chebulic ellagitannins metabolite that exerts antiproliferative and antioxidant activity. Urolithin C exhibit glucose dependent enhancement of insulin secretion in islet cells under normal or dysfunctional conditions. Apparently, it facilitates L-type Ca2+ channel opening and Ca2+ influx into pancreatic β-cells.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Inhae Kang et al.
Molecular nutrition & food research, 60(5), 1129-1138 (2016-02-14)
Urolithins (Uro) are ellagic acid (EA)-derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary
Morgane Bayle et al.
British journal of pharmacology, 176(20), 4065-4078 (2019-08-06)
The pharmacology of polyphenol metabolites on beta-cell function is largely undetermined. We sought to identify polyphenol metabolites that enhance the insulin-secreting function of beta-cells and to explore the underlying mechanisms. INS-1 beta-cells and rat isolated islets of Langerhans or perfused

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