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Merck

SML1998

Sigma-Aldrich

KLH45

≥98% (HPLC)

别名:

N-Cyclohexyl-N-phenethyl-4-(4-(trifluoromethoxy)phenyl)-2H-1,2,3-triazole-2-carboxamide

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About This Item

经验公式(希尔记法):
C24H25F3N4O2
分子量:
458.48
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

oil

顏色

colorless to light yellow

儲存溫度

2-8°C

SMILES 字串

O=C(N(CCC1=CC=CC=C1)C2CCCCC2)N(N=C3)N=C3C4=CC=C(OC(F)(F)F)C=C4

生化/生理作用

KLH45 is an in vivo-active, potent and selective irreversible inhibitor of DDHD2. KLH45 inactivates brain levels of DDHD2 and increases levels of triglycerides in mouse brain.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jordon M Inloes et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(41), 14924-14929 (2014-10-01)
Complex hereditary spastic paraplegia (HSP) is a genetic disorder that causes lower limb spasticity and weakness and intellectual disability. Deleterious mutations in the poorly characterized serine hydrolase DDHD2 are a causative basis for recessive complex HSP. DDHD2 exhibits phospholipase activity

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