跳转至内容
Merck
所有图片(1)

主要文件

SML1707

Sigma-Aldrich

替莫泊芬

≥90% (HPLC)

别名:

3,3′,3′′,3′′′-(7,8-二氢-21H，23H-吗啡-5,10,15,20-四基）四酚, 5,10,15,20-四（间羟基苯）氯

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C44H32N4O4
CAS号:
122341-38-2
分子量:
680.75
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

100

化驗

≥90% (HPLC)

形狀

powder

顏色

dark brown to black

溶解度

DMSO: 2 mg/mL, clear (warmed)

儲存溫度

−20°C

InChI

1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2

InChI 密鑰

LYPFDBRUNKHDGX-UHFFFAOYSA-N

一般說明

替莫卟吩/（四[间羟基苯基]二氢卟酚，m-THPC）是疏水性第二代光敏剂。通过光动力疗法用于晚期头颈癌患者的姑息治疗。

生化／生理作用

替莫卟吩是用于光动力疗法的光敏剂。 替莫卟吩已在临床上用于治疗晚期头颈部鳞状细胞癌，并且正在研究用于其他几种癌症。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
027M4711V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Temoporfin-loaded liposomes: physicochemical characterization
Kuntsche J, et al.
European Journal of Pharmaceutical Sciences, 40(4), 305-315 (2010)
Distribution of temoporfin, a new photosensitizer for the photodynamic therapy of cancer, in a murine tumor model
Whelpton R, et al.
Photochemistry and Photobiology, 61(4), 397-401 (1995)
Amandine Pinto et al.
ACS nano, 15(2), 3251-3263 (2021-01-23)
The dissemination of tumor metastasis in the peritoneal cavity, also called peritoneal metastasis (PM) or carcinomatosis, represents a late stage of gastrointestinal and gynecological cancer with very poor prognosis, even when cytoreductive surgery is effective, due to residual microscopic disease.
Andrej Wagner et al.
Hepatology (Baltimore, Md.), 62(5), 1456-1465 (2015-05-21)
Photodynamic therapy using porfimer (P-PDT) improves palliation and survival in nonresectable hilar bile duct cancer. Tumoricidal penetration depth of temoporfin-PDT (T-PDT) is twice that of P-PDT. In a single-arm phase II study we investigated the safety, efficacy, survival time, and
T Hauge et al.
Photodiagnosis and photodynamic therapy, 13, 330-333 (2015-09-30)
Photodynamic therapy (PDT) in combination with stent have shown promising results in the treatment of biliary tract cancer (BTC) in patients not suitable for surgery. Chemotherapy has been shown to improve survival in patients with local advanced and metastatic BTC.
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门