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Merck
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Key Documents

SML0868

Sigma-Aldrich

嘌吗啡胺

≥98% (HPLC), powder, Hedgehog signaling activator

别名:

2-(1-萘基)-6-(4-吗啉苯胺)-9-环己嘌呤; 9-环己基-N- [4-(4-吗啉基)苯基]-2-(1-萘氧基)-

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About This Item

经验公式(希尔记法):
C31H32N6O2
分子量:
520.62
分類程式碼代碼:
51111800
NACRES:
NA.77

product name

嘌吗啡胺, ≥98% (HPLC)

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 5 mg/mL, clear (warmed)

儲存溫度

−20°C

InChI

1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChI 密鑰

FYBHCRQFSFYWPY-UHFFFAOYSA-N

應用

Purmorphamine已被用于研究Tupfel长鳍株斑马鱼中Hedgehog信号通路上调的影响。

生化/生理作用

Purmorphamine可直接结合Smoothened(Smo)受体,激活Hedgehog(Hh)信号通路。多项研究已经显示,Purmorphamine可诱导成骨细胞的分化、从人胚胎干细胞中产生心肌细胞、增加人纹状体神经干细胞系的神经元分化、以及将人脐带间充质干细胞(hUCMSC)分化成运动神经元。

象形圖

Health hazard

訊號詞

Warning

危險聲明

危險分類

Muta. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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