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Key Documents

SAB4700324

Sigma-Aldrich

Monoclonal Anti-HLA-G-Biotin , (C-terminal) antibody produced in mouse

clone 5A6G7, purified immunoglobulin, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

biotin conjugate

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

5A6G7, monoclonal

形狀

buffered aqueous solution

物種活性

human

濃度

1 mg/mL

技術

flow cytometry: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... HLA-G(3135)

一般說明

The antibody 5A6G7 allows to discriminate between soluble HLA-G protein yielded by shedding from membrane-bound HLA-G forms that do not contain the intron 4-encoded epitope and soluble HLA-G5/HLA-G6 produced from intron 4-retaining alternatively spliced mRNAs. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.

免疫原

C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin

應用

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Monique Lafon et al.
Journal of virology, 79(24), 15226-15237 (2005-11-25)
HLA-G is a nonclassical human major histocompatibility complex class I molecule. It may promote tolerance, leading to acceptance of the semiallogeneic fetus and tumor immune escape. We show here that two viruses-herpes simplex virus type 1 (HSV-1), a neuronotropic virus

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