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Key Documents

SAB3701043

Sigma-Aldrich

Anti-Mouse IgG IgA IgM (H+L) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse

技術

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

運輸包裝

wet ice

儲存溫度

2-8°C

目標翻譯後修改

unmodified

一般說明

Immunoglobulins (Igs) or antibodies are Y-shaped molecules which are the secreted form of the B-cell receptor. Igs are composed of two heavy and two light chains. An immunoglobulin possesses variable (V) domains that bind to antigens and constant (C) domains that bind to effector molecules. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. Pepsin cleaves the carboxy-terminal side of the disulfide bonds in the general region of the antibody and this gives rise to the F(ab′)2 fragment. The two antigen-binding arms of the antibody are linked in this fragment. There are five classes of immunoglobulins- IgM, IgA, IgG, IgD and IgE, classified based on their C regions.

特異性

This product was prepared from polyspecific antiserum by immunoaffinity chromatography using antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Goat Serum, Mouse IgG, Mouse IgA and Mouse IgM.

免疫原

Mouse IgG IgA and IgM whole molecule

物理性質

Antibody format: IgG

外觀

Supplied in 0.1 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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访问文档库

Structure and Function of Immunoglobulins
The Journal of Allergy and Clinical Immunology (2010)
Janeway CA Jr, Travers P, Walport M, et al.
Immunobiology (2001)

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