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物種活性
porcine
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 μIU/mL
standard curve range: 4.69 μIU/ml-300 μIU/ml
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
Porcine ... INS(397415)
一般說明
The antibody reacts specifically against insulin by RIA and immunocytochemistry. It exhibits cross-reactivity with human proinsulin. The antibody binds to insulin with an affinity constant of 8.8 × 109 M-1 in RIA. The insulin gene is mapped to human chromosome 11p15.5.
Human insulin is made up of 51 amino acids. It consists of two peptide chains, 21 amino acids make up A-chain and chain B contains 31 amino acids. The two chains are linked together by a disulfide bond, to form a classical insulin fold with three α helices, chain A having two and one in chain B.
Human insulin is made up of 51 amino acids. It consists of two peptide chains, 21 amino acids make up A-chain and chain B contains 31 amino acids. The two chains are linked together by a disulfide bond, to form a classical insulin fold with three α helices, chain A having two and one in chain B.
應用
请参考Protocol了解详情。
生化／生理作用
Abnormal insulin secretion or function, leads to diabetes mellitus, obesity and other carbohydrate metabolism disorders. Insulin is known to stimulate cell division. The biological effects of insulin are mediated by insulin receptor and it integrates major signaling pathways.
其他說明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Kinetic properties of monoclonal insulin antibodies.
Keilacker H, et al.
Biomedica Biochimica Acta, 45(8), 1093-1102 (1986)
Proinsulin-Specific Monoclonal Antibodies: Immunocytochemical Application as ?-Cell Markers and as Probes for Conversion.
Madsen O D
Diabetes, 36(10), 1203-1211 (1987)
Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.
Ping A J, et al.
American Journal of Human Genetics, 44(5), 720-720 (1989)
The molecular mechanism of insulin action.
Kahn C R
Annual Review of Medicine, 36(1), 429-451 (1985)
Metabolic endotoxemia initiates obesity and insulin resistance.
Cani P D, et al.
Diabetes, 56(7), 1761-1772 (2007)
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