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生物源
bovine nasal septum
品質等級
形狀
powder
技術
cell culture | stem cell: suitable
UniProt登錄號
儲存溫度
−20°C
基因資訊
bovine ... PRG4(280867)
一般說明
蛋白聚糖由核心蛋白组成,糖胺聚糖链与核心蛋白共价连接。它们存在于许多器官和组织中,并在脊椎动物软骨基质中大量存在。蛋白聚糖位于许多细胞的细胞外和细胞周基质中。
應用
牛鼻中隔蛋白多糖含有86%的硫酸软骨素,已用于体外研究硫酸软骨素蛋白多糖的作用。已经证明它可以促进培养物中神经干细胞的存活。
牛鼻中隔蛋白聚糖已被用于诱导小鼠关节炎。
生化/生理作用
蛋白聚糖参与组织结构,促进细胞生长和专门的组织成熟。它们起到生物过滤器的作用,调节胶原纤维的生成、皮肤拉伸强度和神经炎的生长。蛋白聚糖还参与调节生长因子的活性,影响肿瘤细胞的生长和侵袭,并促进角膜透明。
準備報告
通过改良的Antonopoulos程序,在DEAE-纤维素上使用7M尿素进行色谱纯化。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
PloS one, 5(12), e15341-e15341 (2010-12-24)
Understanding how autocrine/paracrine factors regulate neural stem cell (NSC) survival and growth is fundamental to the utilization of these cells for therapeutic applications and as cellular models for the brain. In vitro, NSCs can be propagated along with neural progenitors
Biochimica et Biophysica Acta, 338, 108-119 (1974)
Scientific reports, 9(1), 166-166 (2019-01-19)
We have shown that Raman microspectroscopy is a powerful method for visualization of glycocalyx offering cellular interrogation without staining, unprecedented spatial and spectral resolution, and biochemical information. We showed for the first time that Raman imaging can be used to
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There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.
There are five identified glycosaminoglycan chains (see Figure 1): Hyaluronan is not sulfated, but the other glycosaminoglycan chains contain sulfate substituents at various positions of the chain.
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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