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Merck

P5069

Sigma-Aldrich

前列腺素F2Α氨丁三醇盐α 三羟甲基氨基甲烷盐

synthetic, suitable for cell culture

别名:

(5Z,9α,11α,13E,15S)-9,11,15-三羟基前列腺-5,13-二烯酸 三羟甲基氨基甲烷盐, 前列腺素 f −Tris

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About This Item

经验公式(希尔记法):
C20H34O5 · C4H11NO3
CAS号:
分子量:
475.62
Beilstein:
4087514
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic

品質等級

化驗

≥99%

形狀

powder

技術

cell culture | mammalian: suitable

溶解度

ethanol: 50 mg/mL, clear, colorless

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

NC(CO)(CO)CO.[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)C[C@@H](O)[C@]1([H])\C=C\[C@@H](O)CCCCC

InChI

1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18-,19+;/m0./s1

InChI 密鑰

IYGXEHDCSOYNKY-RZHHZEQLSA-N

基因資訊

human ... PTGFR(5737)

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生化/生理作用

前列腺素 F2α由子宫产生的催产素诱导,作用于黄体引起黄体溶解,抑制孕酮生成。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。也可刺激平滑肌(如支气管)收缩,可能与哮喘有关。这种作用至少部分通过速激肽释放介导。
诱导分娩的溶黄体前列腺素。肺、冠状和脑小动脉床的强效血管收缩剂。子宫内膜 PG F 2α 之间的正反馈环黄体溶解由黄体催产素完成

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Kurt J Sales et al.
Biochimica et biophysica acta, 1793(12), 1917-1928 (2009-10-13)
Pro-inflammatory mediators, like prostaglandin (PG) and chemokines, promote tumourigenesis by enhancing cell proliferation, migration of immune cells and recruitment of blood vessels. Recently we showed elevated expression of the chemokine (C-X-C motif) receptor 2 (CXCR2) in endometrial adenocarcinomas localized to
Matthew Elmes et al.
Physiological reports, 3(4) (2015-04-17)
Advanced maternal age of first time pregnant mothers is associated with prolonged and dysfunctional labor and significant risk of emergency cesarean section. We investigated the influence of maternal age on myometrial contractility, expression of contractile associated proteins (CAPs), and global
Augusta Zannoni et al.
Reproductive biology and endocrinology : RB&E, 5, 31-31 (2007-07-31)
The corpus luteum (CL) is a transient endocrine gland and prostaglandin F2-alpha is considered to be the principal luteolysin in pigs. In this species, the in vivo administration of prostaglandin F2-alpha induces apoptosis in large vessels as early as 6
Jeffrey R Sommer et al.
Animal reproduction science, 100(3-4), 402-410 (2006-11-23)
An efficient protocol was developed to synchronize and superovulate mature pigs for the collection of pronuclear stage embryos suitable for DNA microinjection. A timed and coordinated regimen of Lutalyse, PG600 and Chorulon along with daily checking for estrus allowed synchronization
G J Nie et al.
American journal of veterinary research, 62(8), 1285-1289 (2001-08-11)
To determine whether administration of a microdose of prostaglandin at the BAI HUI acupuncture point offers any advantage over IM injections for luteolysis, ovulatory interval, or systemic response in mares. 17 mature cycling mares, 3 to 20 years of age

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